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Heart Biomarker Evaluation in Apnea Treatment

Name Label Folder
clusterid
Recoded Site Identifier
Recoded Site Identifier

The original site identifier was removed from the dataset because it was considered identifiable.

Administrative
followup_visit_date
Date of the follow-up visit
Date of the follow-up visit Administrative
nsrrid
NSRR Subject Identifier
NSRR Subject Identifier

This obfuscated subject ID was created by the National Sleep Research Resource (NSRR) team to more easily match with file downloads.

Administrative
timepoint
Visit number
Visit number Administrative
treatmentarm
Treatment Arm
Treatment Arm

1. HLSE (Healthy Lifestyles and Sleep Education - control arm. 2. HLSE-O (Healthy Lifestyles and Sleep Education + (supplemental nocturnal) Oxygen - oxygen arm. 3. HLSE-P (Healthy Lifestyles and Sleep Education + Positive airway pressure treatment -Continuous Positive Airway Pressure (CPAP) arm)

Administrative/Randomization
agecat
Age category
Age category

Created using values from the calc_age variable

Demographics
calc_age
Age
Age Demographics
ethnicity
Ethnicity
Ethnicity Demographics
male
Gender
Gender Demographics
race3
Race
Race

Presented as three (3) categories based on suggested Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) de-identification procedures.

Demographics
diaallmean
Average Diastolic Pressure (all readings)
Average Diastolic Pressure (all readings) Measurements/Ambulatory Blood Pressure
heartallmean
Average Heart Rate (all readings)
Average Heart Rate (all readings) Measurements/Ambulatory Blood Pressure
sysallmean
Average Systolic Pressure (all readings)
Average Systolic Pressure (all readings) Measurements/Ambulatory Blood Pressure
bmi
Body mass index (BMI)
Body mass index (BMI) Measurements/Anthropometry
heightcm
Height
Height Measurements/Anthropometry
hipmean
Hip Circumference Mean (2 Measurements)
Hip Circumference Mean (2 Measurements) Measurements/Anthropometry
neckmean
Neck Circumference Mean (2 Measurements)
Neck Circumference Mean (2 Measurements) Measurements/Anthropometry
waistmean
Waist Circumference Mean (2 Measurements)
Waist Circumference Mean (2 Measurements) Measurements/Anthropometry
weightkg
Weight
Weight Measurements/Anthropometry
aphypi
Overall Apnea-Hypopnea Index (AHI) from Embletta Sleep Report
Overall Apnea-Hypopnea Index (AHI) from Embletta Sleep Report Measurements/Embletta
diasmean
Diastolic Blood Pressure (BP) Mean (3 Measurements)
Diastolic Blood Pressure (BP) Mean (3 Measurements) Measurements/Seated Blood Pressure
pulsemean
Pulse Mean (3 Measurements)
Pulse Mean (3 Measurements) Measurements/Seated Blood Pressure
sysmean
Systolic Blood Pressure (BP) Mean (3 Measurements)
Systolic Blood Pressure (BP) Mean (3 Measurements) Measurements/Seated Blood Pressure
phqtotal
Patient Health Questionnaire-9 (PHQ-9): Total score
Patient Health Questionnaire-9 (PHQ-9): Total score

The sum of items 1 through 9

Questionnaires/PHQ-9
excl05_escore
Epworth Sleepiness Scale (ESS) score at screening
Epworth Sleepiness Scale (ESS) score at screening Administrative/Eligibility
exclusion06
Current or past oxygen or Continuous Positive Airway Pressure (CPAP) use
Current or past oxygen or Continuous Positive Airway Pressure (CPAP) use Administrative/Eligibility
incl01_age
Age of participant at screening
Age of participant at screening Administrative/Eligibility
incl04_angio
Established coronary artery disease (CAD): Angiostenosis
Established coronary artery disease (CAD): Angiostenosis Administrative/Eligibility
incl04_bmi30
Coronary artery disease (CAD) risk factors: Body mass index (BMI) greater than 30
Coronary artery disease (CAD) risk factors: Body mass index (BMI) greater than 30 Administrative/Eligibility
incl04_carp
Established coronary artery disease (CAD): Coronary artery revascularization procedure (CARP)
Established coronary artery disease (CAD): Coronary artery revascularization procedure (CARP) Administrative/Eligibility
incl04_diab
Coronary artery disease (CAD) risk factors: Diabetes
Coronary artery disease (CAD) risk factors: Diabetes Administrative/Eligibility
incl04_dyslipid
Coronary artery disease (CAD) risk factors: Dyslipidemia
Coronary artery disease (CAD) risk factors: Dyslipidemia Administrative/Eligibility
incl04_htn
Coronary artery disease (CAD) risk factors: Hypertension (HTN)
Coronary artery disease (CAD) risk factors: Hypertension (HTN) Administrative/Eligibility
incl04_priormi
Established coronary artery disease (CAD): Prior myocardial infarction (MI)
Established coronary artery disease (CAD): Prior myocardial infarction (MI) Administrative/Eligibility
incl05_bscore
Berlin scale score at screening
Berlin scale score at screening Administrative/Eligibility
inclusion04
Established coronary artery disease (CAD) or risk factors
Established coronary artery disease (CAD) or risk factors Administrative/Eligibility
inclusion05
Berlin score greater than 2
Berlin score greater than 2 Administrative/Eligibility
rctsource
Recruitment source
Recruitment source Administrative/Eligibility
cadpresent
Presence of established coronary artery disease (CAD)
Presence of established coronary artery disease (CAD) Administrative/Randomization
bmi_scrn
Body mass index (BMI) at screening visit
Body mass index (BMI) at screening visit

Hand-calculated using self-reported height and weight from the Berlin Questionnaire

Administrative/Screening Visit
bothered
Has your snoring bothered other people?
Has your snoring bothered other people?

Question from the Berlin Questionnaire

Administrative/Screening Visit
bscore
Hand-calculated Berlin Score
Hand-calculated Berlin Score

Hand-calculated Berlin score from the Berlin Questionnaire

Administrative/Screening Visit
dinner
Chance of dozing while at the dinner table
Chance of dozing while at the dinner table

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
doyousnore
Do you snore?
Do you snore?

Question from the Berlin Questionnaire

Administrative/Screening Visit
driving
Chance of dozing while driving
Chance of dozing while driving

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
escore
Epworth Sleepiness Scale (ESS) Score
Epworth Sleepiness Scale (ESS) Score

Total Epworth Sleepiness Scale (ESS) score from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
feeltired
How often do you feel tired or fatigued after your sleep?
How often do you feel tired or fatigued after your sleep?

Question from the Berlin Questionnaire

Administrative/Screening Visit
highbp
Do you have high blood pressure (BP)
Do you have high blood pressure (BP)

Question from the Berlin Questionnaire

Administrative/Screening Visit
inact
Chance of dozing while sitting, inactive, in a public place
Chance of dozing while sitting, inactive, in a public place

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
lying
Chance of dozing while lying down to rest
Chance of dozing while lying down to rest

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
nodded
Have you ever nodded off or fallen asleep while driving a vehicle?
Have you ever nodded off or fallen asleep while driving a vehicle?

Question from the Berlin Questionnaire

Administrative/Screening Visit
nodoften
If yes, how often does this occur
If yes, how often does this occur

Question from the Berlin Questionnaire

Administrative/Screening Visit
oftensnore
How often do you snore
How often do you snore

Question from the Berlin Questionnaire

Administrative/Screening Visit
passeng
Chance of dozing as a passenger in a car for more than an hour without a break
Chance of dozing as a passenger in a car for more than an hour without a break

Question for the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
quitbreath
Has anyone noticed that you quit breathing during your sleep?
Has anyone noticed that you quit breathing during your sleep?

Questionnaire from the Berlin Questionnaire

Administrative/Screening Visit
sitquiet
Chance of dozing while sitting quietly after lunch
Chance of dozing while sitting quietly after lunch

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
sitread
Chance of dozing while sitting and reading
Chance of dozing while sitting and reading

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
sittalk
Chance of dozing while sitting and talking to someone
Chance of dozing while sitting and talking to someone

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
smoke
Do you smoke in the bedroom?
Do you smoke in the bedroom? Administrative/Screening Visit
snoringis
Your snoring is?
Your snoring is?

Question from the Berlin Questionnaire

Administrative/Screening Visit
stopped
Chance of dozing while in a car while stopped
Chance of dozing while in a car while stopped

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
useoxy
Do you use oxygen, Continous Positive Airway Pressure (CPAP), or BiLevel Positive Airway Pressure (BiPAP)
Do you use oxygen, Continous Positive Airway Pressure (CPAP), or BiLevel Positive Airway Pressure (BiPAP) Administrative/Screening Visit
wakingtime
During your waketime, do you feel tired, fatigued or not up to par?
During your waketime, do you feel tired, fatigued or not up to par?

Question from the Berlin Questionnaire

Administrative/Screening Visit
watchtv
Chance of dozing while watching TV
Chance of dozing while watching TV

Question from the Epworth Sleepiness Scale (ESS)

Administrative/Screening Visit
adverseevent
Withdrawal Reason: Adverse Event or Serious Adverse Event
Withdrawal Reason: Adverse Event or Serious Adverse Event Administrative/Withdrawal
ahihigh
Withdrawal Reason: Apnea-Hypopnea Index (AHI) greater than 50
Withdrawal Reason: Apnea-Hypopnea Index (AHI) greater than 50 Administrative/Withdrawal
ahilow
Withdrawal Reason: Apnea-Hypopnea Index (AHI) less than 15
Withdrawal Reason: Apnea-Hypopnea Index (AHI) less than 15 Administrative/Withdrawal
centap
Withdrawal Reason: Central sleep apnea index greater than 5
Withdrawal Reason: Central sleep apnea index greater than 5 Administrative/Withdrawal
dateofwithdrawal
Withdrawal: Date of Withdrawal or Removal
Withdrawal: Date of Withdrawal or Removal Administrative/Withdrawal
dissatisfaction
Withdrawal Reason: Dissatisfaction with treatment
Withdrawal Reason: Dissatisfaction with treatment Administrative/Withdrawal
failpm
Withdrawal Reason: Unable to complete successful portable monitor
Withdrawal Reason: Unable to complete successful portable monitor Administrative/Withdrawal
illness
Withdrawal Reason: Significant concurrent illness
Withdrawal Reason: Significant concurrent illness Administrative/Withdrawal
lastvisit
Withdrawal: Last visit completed
Withdrawal: Last visit completed Administrative/Withdrawal
lossinterest
Withdrawal Reason: Loss of interest in the study
Withdrawal Reason: Loss of interest in the study Administrative/Withdrawal
lostfollowup
Withdrawal Reason: Lost to follow-up
Withdrawal Reason: Lost to follow-up Administrative/Withdrawal
noncompliance
Withdrawal Reason: Protocol non-compliance
Withdrawal Reason: Protocol non-compliance Administrative/Withdrawal
nopm
Withdrawal Reason: Did not wear portable monitor
Withdrawal Reason: Did not wear portable monitor Administrative/Withdrawal
oxysat
Withdrawal Reason: Nocturnal oxygen saturation low
Withdrawal Reason: Nocturnal oxygen saturation low Administrative/Withdrawal
relocation
Withdrawal Reason: Relocation
Withdrawal Reason: Relocation Administrative/Withdrawal
withdrawnconsent
Withdrawal Reason: Withdrawn consent
Withdrawal Reason: Withdrawn consent Administrative/Withdrawal
withother
Withdrawal Reason: Other reason
Withdrawal Reason: Other reason Administrative/Withdrawal
bp24date
Date of 24 hour blood pressure (BP)
Date of 24 hour blood pressure (BP) Measurements/Ambulatory Blood Pressure
bp24endtime
End time
End time Measurements/Ambulatory Blood Pressure
bp24starttime
Start time
Start time Measurements/Ambulatory Blood Pressure
diaallmax
Maximum Diastolic Pressure (all readings)
Maximum Diastolic Pressure (all readings) Measurements/Ambulatory Blood Pressure
diaallmin
Minimum Diastolic Pressure (all readings)
Minimum Diastolic Pressure (all readings) Measurements/Ambulatory Blood Pressure
diaallsd
Standard Deviation of Diastolic Pressure (all readings)
Standard Deviation of Diastolic Pressure (all readings) Measurements/Ambulatory Blood Pressure
dianondip
Less than 10% diastolic dipping from wake to sleep
Less than 10% diastolic dipping from wake to sleep Measurements/Ambulatory Blood Pressure
dianondipping
Less than 10% diastolic dipping from wake to sleep
Less than 10% diastolic dipping from wake to sleep Measurements/Ambulatory Blood Pressure
diaratiovalid
Ratio of diastolic between sleep and wake with valid sleep and wake
Ratio of diastolic between sleep and wake with valid sleep and wake Measurements/Ambulatory Blood Pressure
diasleepmax
Maximum Diastolic Pressure (asleep)
Maximum Diastolic Pressure (asleep) Measurements/Ambulatory Blood Pressure
diasleepmean
Average Diastolic Pressure (asleep)
Average Diastolic Pressure (asleep) Measurements/Ambulatory Blood Pressure
diasleepmin
Minimum Diastolic Pressure (asleep)
Minimum Diastolic Pressure (asleep) Measurements/Ambulatory Blood Pressure
diasleepsd
Standard Deviation of Diastolic Pressure (asleep)
Standard Deviation of Diastolic Pressure (asleep) Measurements/Ambulatory Blood Pressure
diasleepvalid
Mean of diastolic readings with valid sleep
Mean of diastolic readings with valid sleep Measurements/Ambulatory Blood Pressure
diaswratio
Ratio of diastolic between sleep and wake
Ratio of diastolic between sleep and wake Measurements/Ambulatory Blood Pressure
diawakemax
Maximum Diastolic Pressure (wake)
Maximum Diastolic Pressure (wake) Measurements/Ambulatory Blood Pressure
diawakemean
Average Diastolic Pressure (wake)
Average Diastolic Pressure (wake) Measurements/Ambulatory Blood Pressure
diawakemin
Minimum Diastolic Pressure (wake)
Minimum Diastolic Pressure (wake) Measurements/Ambulatory Blood Pressure
diawakesd
Standard Deviation of Diastolic Pressure (wake)
Standard Deviation of Diastolic Pressure (wake) Measurements/Ambulatory Blood Pressure