Heart Biomarker Evaluation in Apnea Treatment

The original site identifier was removed from the dataset because it was considered identifiable.

This obfuscated subject ID was created by the National Sleep Research Resource (NSRR) team to more easily match with file downloads.

1. HLSE (Healthy Lifestyles and Sleep Education - control arm. 2. HLSE-O (Healthy Lifestyles and Sleep Education + (supplemental nocturnal) Oxygen - oxygen arm. 3. HLSE-P (Healthy Lifestyles and Sleep Education + Positive airway pressure treatment -Continuous Positive Airway Pressure (CPAP) arm)

Created using values from the calc_age variable

Summary score for Patient Health Questionnaire 9-item. Each item is scored from 0 to 3, while the total score range from 0 to 27. The PHQ-9 score can be divided into the following categories of increasing severity: minimal (0-4), mild (5-9), moderate (10-14), moderately severe (15-19), and severe (20-27). Kroenke K et al. 2001 (PubMED ID: 11556941)

Search for all PHQ-9 variables within this dataset

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bmi at Baseline

Average resting diastolic blood pressure of three measurements collected from the upper arm in a single clinic visit. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: diasmean at Baseline

Average resting systolic blood pressure of three measurements collected from the upper arm in a single clinic visit. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sysmean at Baseline

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: calc_age at Baseline

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: calc_age at Baseline

Original missing value is recoded as "not reported".

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: ethnicity

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: race7

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: male

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: smoked , smokedmonth at Baseline

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: smoked at Baseline

Harmonized by the NSRR team.

Data collected with no EEGs. Refer to the source for detailed definition for respiratory events: ahi_screening at Baseline

Estimated sleep duration, providing an approximation of total sleep duration (i.e. total sleep time) inferred from analysis of non-EEG channels Zhao et al., 2017 (PMID:27707441)

Harmonized by the NSRR team. Source: index_time at Baseline

Calculated - Summary metric of sleep disordered breathing events from the baseline screening visit.

Estimated sleep duration, providing an approximation of total sleep duration (i.e. total sleep time) inferred from analysis of non-EEG channels Zhao et al., 2017 (PMID:27707441)

There is a HeartBEAT specific respiratory event index measure aphypi. Details can be found in the Embletta scoring manual.

Calculated - Total score based on an 8-item questionnaires ranking likelihood of dozing off Johns MW 1991 (PubMed ID: 1798888). Scale 0-3 for individual items; 0 to 24 for overall score.

Search for all ESS variables within this dataset

Hand-calculated using self-reported height and weight from the Berlin Questionnaire

Average direction of electrical activity during the P wave

Duration of atrial depolarization

Duration from the beginning of the P-wave to the beginning of the QRS complex

Average direction of electrical activity during the QRS complex

duration from the end of the PR interval to the end of the S wave

QRS complex wider than .12 seconds

QRS complex wider than .12 seconds