Name
aphypis
Label
Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Description

Estimated sleep duration, providing an approximation of total sleep duration (i.e. total sleep time) inferred from analysis of non-EEG channels Zhao et al., 2017 (PMID:27707441)

Details about how the respiratory events were scored can be found in the Embletta scoring manual.

Please refer to ahi_screening from the baseline screening visit for a more standardized version of AHI in this study.

Units
events per hour
Type
numeric
Visit number vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
N Mean StdDev Median Min Max Unknown Total
Baseline 294 36.5 ± 20.0 33.4 0.0 95.4 24 318
Follow-up 264 22.5 ± 21.0 16.3 0.0 94.7 37 301
Treatment Arm vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Baseline
N Mean StdDev Median Min Max Unknown Total
Total 294 36.5 ± 20.0 33.4 0.0 95.4 24 318
Healthy Lifestyles and Sleep Education - control arm (HLSE) 99 35.9 ± 21.3 32.1 0.0 95.4 7 106
Healthy Lifestyles and Sleep Education + (supplemental nocturnal) Oxygen - oxygen arm (HLSE-O) 97 33.7 ± 18.8 28.2 0.0 86.3 9 106
Healthy Lifestyles and Sleep Education + Positive airway pressure treatment - CPAP arm (HLSE-P) 98 39.9 ± 19.3 39.1 0.0 89.6 8 106
Treatment Arm vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Follow-up
N Mean StdDev Median Min Max Unknown Total
Total 264 22.5 ± 21.0 16.3 0.0 94.7 37 301
Healthy Lifestyles and Sleep Education - control arm (HLSE) 90 33.9 ± 24.5 31.4 0.0 94.7 10 100
Healthy Lifestyles and Sleep Education + (supplemental nocturnal) Oxygen - oxygen arm (HLSE-O) 90 17.8 ± 16.3 13.4 0.0 73.5 11 101
Healthy Lifestyles and Sleep Education + Positive airway pressure treatment - CPAP arm (HLSE-P) 84 15.1 ± 15.9 10.5 0.0 70.8 16 100
Age category vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Baseline
N Mean StdDev Median Min Max Unknown Total
Total 294 36.5 ± 20.0 33.4 0.0 95.4 24 318
45-54 years 50 36.0 ± 20.0 32.6 0.0 80.3 3 53
55-64 years 130 35.3 ± 20.5 30.9 0.0 95.4 9 139
65 years or older 114 38.2 ± 19.3 36.2 0.0 91.1 12 126
Age category vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Follow-up
N Mean StdDev Median Min Max Unknown Total
Total 264 22.5 ± 21.0 16.3 0.0 94.7 36 300
45-54 years 40 22.9 ± 19.7 18.7 0.0 70.2 9 49
55-64 years 113 21.1 ± 22.3 14.5 0.0 94.7 14 127
65 years or older 111 23.7 ± 20.3 20.1 0.0 78.4 13 124
Gender of the participant vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Baseline
N Mean StdDev Median Min Max Unknown Total
Total 294 36.5 ± 20.0 33.4 0.0 95.4 24 318
Female 79 32.5 ± 17.5 27.6 0.0 73.6 5 84
Male 215 38.0 ± 20.6 34.9 0.0 95.4 19 234
Gender of the participant vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Follow-up
N Mean StdDev Median Min Max Unknown Total
Total 264 22.5 ± 21.0 16.3 0.0 94.7 37 301
Female 71 17.5 ± 16.7 11.9 0.0 70.8 8 79
Male 193 24.3 ± 22.2 18.4 0.0 94.7 29 222
Race of the participant vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Baseline
N Mean StdDev Median Min Max Unknown Total
Total 293 36.6 ± 20.0 33.6 0.0 95.4 24 317
White 237 38.2 ± 19.7 35.4 0.0 95.4 19 256
American Indian or Alaskan Native 2 25.8 ± 8.8 25.8 19.5 32.0 - 2
Black or African American 38 27.7 ± 19.9 21.7 0.0 80.3 5 43
Asian 6 28.3 ± 17.1 24.9 8.2 54.2 - 6
Native Hawaiian or other Pacific islander 1 37.8 - 37.8 37.8 37.8 - 1
Other 4 43.3 ± 14.4 45.3 24.0 58.5 - 4
Multiple 5 35.0 ± 30.3 27.3 11.0 84.6 - 5
Race of the participant vs Respiratory Event Index (Supine): (All respiratory events with at least 50% flow reduction and without any oxygen desaturation threshold used) / hours of estimated sleep in supine position from type III home sleep apnea test
Follow-up
N Mean StdDev Median Min Max Unknown Total
Total 263 22.5 ± 21.1 16.3 0.0 94.7 36 299
White 213 23.9 ± 21.7 18.5 0.0 94.7 28 241
American Indian or Alaskan Native 2 9.3 ± 7.5 9.3 4.0 14.6 - 2
Black or African American 33 12.4 ± 13.2 9.8 0.0 67.8 8 41
Asian 6 26.8 ± 15.2 26.8 3.0 50.6 - 6
Native Hawaiian or other Pacific islander 1 37.5 - 37.5 37.5 37.5 - 1
Other 3 15.5 ± 19.3 9.4 0.0 37.1 - 3
Multiple 5 33.9 ± 28.9 21.9 4.8 79.0 - 5