Cleveland Family Study

4.1 Background and Rationale

The Familial Aggregation and Natural History of Sleep Apnea study is a genetic-epidemiologic study of Obstructive Sleep Apnea. The Laboratory for Clinical Biochemistry Research (LCBR) will have responsibilities for special urine collection and handling protocols as well as training and QC monitoring. The laboratory will also be responsible for performing assays and reporting results.

The urine samples collected and processed by General Clinical Research Center (GCRC) technicians are the foundation for many of these tests. The most important step (and potentially the most variable) in these tests is the collection and processing of the urine samples. If the urine sample itself is not correctly drawn and processed, the laboratory results may not be precise or may not be valid.