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Blog | michaelprerau

ENIGMA-Sleep working group: An international sleep collaboration

What is the ENIGMA-Sleep? The Enhancing NeuroImaging Genetics through Meta Analysis (ENIGMA) consortium is a global collaboration of over 1400 scientists across 43 countries, studying neuropsychiatric illnesses and provides a powerful collaborative framework around the world. ENIGMA has more than 50 working groups, pooling large-scale coordinated data and expertise to answer fundamental clinical and neuroscientific questions, which offers testing reproducibility and robustness of findings (1). Keep reading

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By michaelprerau on September 20, 2021 Sep 20, 2021 in Guest Blogger

Arousal Burden is Linked with Long-Term Cardiovascular and All-Cause Mortality

Guest Blogger: Mattias Baumert Overview What is the problem being addressed? Our objective was to quantify the burden of cortical arousals throughout sleep and determine its association with long-term cardiovascular (CV) and overall mortality. What was the approach to solving the problem? We quantified arousal burden (AB) as the cumulative duration of all arousal events relative to total sleep time in three large cohort studies. Keep reading

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By michaelprerau on June 16, 2021 Jun 16, 2021 in Guest Blogger

AHI Uncertainty: How Many Patients are Being Denied Treatment Due to Chance?

A patient's apnea-hypopnea index (AHI) determines whether or not they are eligible for reimbursable treatment. But how certain can we be that a patient's AHI is actually above or below a clinical threshold? In this study using 2049 subjects from MESA dataset from NSRR, we develop a metric for computing a confidence interval around a patient's AHI. Keep reading

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By michaelprerau on November 16, 2020 Nov 16, 2020 in Showcase