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MrOS Sleep Study


Ancillary study that focuses on understanding the relationship between sleep disorders and falls, fractures, mortality, and vascular disease.


2,911 men 65 years or older.


Two sleep study cycles, 2003-2005 and 2009-2012.


National Institutes of Health

About the Study

MrOS is an ancillary study of the parent Osteoporotic Fractures in Men Study. Between 2000 and 2002, 5,994 community-dwelling men 65 years or older were enrolled at 6 clinical centers in a baseline examination. Between December 2003 and March 2005, 3,135 of these participants were recruited to the Sleep Study when they underwent full unattended polysomnography and 3 to 5-day actigraphy studies. The objectives of the Sleep Study are to understand the relationship between sleep disorders and falls, fractures, mortality, and vascular disease.

The MrOS dataset on NSRR is limited in scope (e.g. no actigraphy raw data or results are included), with its primary focus being polysomnography (PSG) data. MrOS Online is a publicly available resource that contains additional sleep variables and data from other MrOS research visits. For more information on the MrOS cohort, contact the San Francisco Coordinating Center.

Citation and acknowledgement

When using this dataset, please cite the following:

Zhang GQ, Cui L, Mueller R, Tao S, Kim M, Rueschman M, Mariani S, Mobley D, Redline S. The National Sleep Research Resource: towards a sleep data commons. J Am Med Inform Assoc. 2018 Oct 1;25(10):1351-1358. doi: 10.1093/jamia/ocy064. PMID: 29860441; PMCID: PMC6188513.

Blackwell T, Yaffe K, Ancoli-Israel S, Redline S, Ensrud KE, Stefanick ML, Laffan A, Stone KL; Osteoporotic Fractures in Men Study Group. Associations between sleep architecture and sleep-disordered breathing and cognition in older community-dwelling men: the Osteoporotic Fractures in Men Sleep Study. J Am Geriatr Soc. 2011 Dec;59(12):2217-25. doi: 10.1111/j.1532-5415.2011.03731.x. Epub 2011 Nov 7. PMID: 22188071; PMCID: PMC3245643.

Please include the following text in the Acknowledgements:

The National Heart, Lung, and Blood Institute provided funding for the ancillary MrOS Sleep Study, "Outcomes of Sleep Disorders in Older Men," under the following grant numbers: R01 HL071194, R01 HL070848, R01 HL070847, R01 HL070842, R01 HL070841, R01 HL070837, R01 HL070838, and R01 HL070839. The National Sleep Research Resource was supported by the National Heart, Lung, and Blood Institute (R24 HL114473, 75N92019R002).

Data overview

/datasets (introduction)
Core data from MrOS Sleep Visit 1 and Visit 2.

/polysomnography (introduction)
Overnight polysomnography (PSG) data from MrOS Sleep Visit 1 and Visit 2.

Protocols and Manuals


HRV Analysis

As part of Ancillary Study #108, researchers at Case Western Reserve University performed heart rate variability analysis on MrOS Sleep Visit 1 data. Read more about the methods and browse the result variables.

Recent Changes

National Sleep Research Resource
MrOS Sleep Study