Multi-center longitudinal investigation of factors associated with cardiovascular disease
6,814 black, white, Hispanic, and Chinese-American men and women
2000 to present
National Heart, Lung, and Blood Institute
Multi-Ethnic Study of Atherosclerosis (MESA) is an NHLBI-sponsored 6-center collaborative longitudinal investigation of factors associated with the development of subclinical cardiovascular disease and the progression of subclinical to clinical cardiovascular disease in 6,814 black, white, Hispanic, and Chinese-American men and women initially ages 45-84 at baseline in 2000-2002. There have been four follow-up exams to date, in the years 2003-2004, 2004-2005, 2005-2007, and 2010-2011. Between 2010-2012, 2,237 participants also were enrolled in a Sleep Exam (MESA Sleep) which included full overnight unattended polysomnography, 7-day wrist-worn actigraphy, and a sleep questionnaire. The objectives of the sleep study are to understand how variations in sleep and sleep disorders vary across gender and ethnic groups and relate to measures of subclinical atherosclerosis.
MESA Sleep data are made available in collaboration with the MESA Coordinating Center. We have made polysomnography and actigraphy raw data available for download, along with key sets of MESA Sleep covariates. If you wish to access data from other MESA exams, please visit the BioLINCC MESA Collection or contact the MESA Coordinating Center.
Find a complete list of changes in the CHANGELOG.md
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MESA is supported by NHLBI funded contracts HHSN268201500003I, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute, and by cooperative agreements UL1-TR-000040, UL1-TR-001079, and UL1-TR-001420 funded by NCATS. MESA Sleep was supported by NHLBI R01 L098433.