Hispanic Community Health Study / Study of Latinos

This variable is the field center that was derived from the city of origin.

This is the age of the participant in years at the time of the participant's clinic visit.

This variable describes the participant's gender.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bmi at Visit 1

Average resting diastolic blood pressure of three measurements collected from the upper arm in a single clinic visit. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sbpa6 at Visit 1

Average resting systolic blood pressure of three measurements collected from the upper arm in a single clinic visit. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sbpa5 at Visit 1

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 1

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 1

All subjects are Hispanic or Latino.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bkgrd1_c7

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: race

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: gendernum

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: current_smoker at Visit 1

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: cigarette_use

Harmonized by the NSRR team.

Data collected with no EEGs. Refer to the source for detailed definition for respiratory events: slpa54 at Visit 1

Harmonized by the NSRR team.

Data collected with no EEGs. Refer to the source for detailed definition for respiratory events: slpa63 at Visit 1

Thi variable combines the 3 permission variables to determine whether or not a study participant gave any permission for public use of data.

This variable is the field center that was derived from the city of origin.

This variable determines whether or not a study participant gave permission for use for for-profit use of study data.

This variable determines whether or not a study participant consented to participate in the baseline examination study.

This variable determines whether or not a study participant had blood draws successfully conducted without incidents or problems for tubes 4 and 5 to make DNA available to investigators associated or not associated to HCHS/SOL and specialized laboratories.

This variable determines whether or not a study participant gave permission for use for investigators outside HCHS/SOL.

This variable defines a participant as meeting all requirements to determine if eligible for annual follow-up.

This variable determines whether or not a study participant fully consented to genotyping for use with investigators associated or not associated to HCHS/SOL and specialized laboratories.

This variable determines whether or not a study participant gave permission for non-profit use of study data.

This variable is an indicator of household sample address allocation and distribution for HCHS/SOL recruitment.

This variable is the sample design list household frame count variable used in statistical analyses.

This variable is the sample design variable used in statistical analyses.

This variable is the sample design clustering household frame count variable used in statistical analyses.

This variable is the sample design clustering variable used in statistical analyses as the cluster variable that is combination of the field center and selected block group identifier.

This variable is the sample design stratification variable used in statistical analyses as the stratum variable that is a combination of field center, Hispanic household proportion, and SES.

This variable is the sample design stratification household frame variable used in statistical analyses.

The calibrated sample weight is the calibrated, trimmed, non-response adjusted reciprocal of a participant's probability of selection into the HCHS/SOL study. The trimmed, nonresponse adjusted sample weights were calibrated using first the 7-category Hispanic Background distribution and then the 12-category age group/gender distribution using the 2010 Decennial Census. This variable is used for analyses purposes only.

The FC-specific normalized sample weight is the field center specific normalized, calibrated, trimmed, non-response adjusted (household and person-level) reciprocal of a participant's probability of selection into the HCHS/SOL study. The calibrated, trimmed, non-response adjusted sample weights were normalized using the weighted mean divided by weighted standard deviation calculated for each field center separately and used to normalize the expanded calibrated sample weights (WEIGHT_Final_Norm_Center). This final sample weight variable is used for analyses purposes only when the subpopulation is restricted to within a single site.

The normalized sample weight is the overall normalized, calibrated, trimmed, nonresponse adjusted (household and person-level) reciprocal of a participant's probability of selection into the HCHS/SOL study. The base sample weights, i.e. the reciprocal of a participant's probability of selection into the HCHS/SOL study, were first adjusted by household-level and person-level non-response. The non-response adjusted sample weights were then trimmed using the selected average percentile that minimizes model MSE within each field center. All sample weights that fell above the selected percentile were trimmed to the selected percentile and the trimmed difference was evenly distributed among all of the non-trimmed sample weights. The trimmed, non-response adjusted sample weights were then calibrated using first the 7-category Hispanic Background distribution and then the 12-category age group/gender distribution using the 2010 Decennial Census. Finally, these calibrated, trimmed, non-response adjusted sample weights were normalized using the weighted mean divided by weighted standard deviation of the entire HCHS/SOL sample to normalize the expanded calibrated sample weights (WEIGHT_Final_Norm_Overall). This final sample weight variable is used for analyses purposes only.

This variable is created using the calculated body mass index to define categories based on current WHO (World Health Organization) classifications

This variable is created using the calculated body mass index to define categories based on current WHO (World Health Organization) classifications

This variable is created using the calculated body mass index to define categories based on current WHO (World Health Organization) classifications

This variable is created using the calculated body mass index to define categories based on current WHO (World Health Organization) classifications

During two time periods the standing height as measured at the Bronx site was incorrect due to a mis-mounted stadiometer used in measuring all participants. The derived variable was implemented based on a recommendation from the Quality Control subcommittee.

This variable is based on the empirical evidence from the spirometry that the ratio of FEV1 to FVC is below the level defined by the ATS as indicative of restricted airflow. Defined only for valid spirometries.

This variable is based on the empirical evidence from the spirometry that the ratio of FEV1 to FVC is below the level defined by the ATS as indicative of restricted airflow.

This variable combines scanned/transcribed anti-asthmatic medication use with self-report asthma medication use.

This variable is based on the post-bronchodilator measurement of the FEV1. The airflow remains restricted after the administration of albuterol the person did not respond by greater than a 15% improvement over their first measurement. If PRBA29 is not missing and POBA29 is not missing and PRBA29 > 0 then.

This indicator of COPD is based on the post-bronchodilator measurement of the FEV1 to FVC ratio. The airflow remains restricted after the administration of albuterol.

This variable is based on the post-bronchodilator measurement of the FEV1 to FVC ratio. The airflow remains restricted after the administration of albuterol. This variable is also defined for all participants who did not conduct a post-spirometry exam. Defined only for valid spirometries.

This variable combines scanned/transcribed anti-asthmatic medication use with self-report COPD medication use.

This variable is the ratio of forced expiratory volume in one minute (FEV1 ) to forced vital capacity (FVC) expressed as a percentage.

This variable is a flag for whether a post bronchodilator was expected, based on the premeasurement. A post measurement was expected if the FEV1 to FVC ratio was less than 70% or less than the lower limit of normal for FEV1/FVC%.

This variable is based on the ratio of the measured FEV1 difference from postbronchodilator and pre-bronchodilator exams over the Predicted FEV1 calculated prebronch (both values must be non-missing, and the post-bronchodilator spirometry examinations must be valid).

This variable is based on the ratio of the measured FEV1 difference from postbronchodilator and pre-bronchodilator exams over the Predicted FEV1 calculated prebronch (both values must be non-missing, and the post-bronchodilator spirometry examination must be valid) among participants with pre FEV1/FVC<70 only (ignores LLN comparison).

This variable is an overall data quality indicator derived by the pulmonary reading center on the adequacy study for use.

This variable is an overall data quality indicator derived by the pulmonary reading center on the adequacy study for use.

This variable is a flag for whether a post bronchodilator was valid (grade A-D). Defined only for participants where a post measurement was expected.

This variable is for the score of the digit symbol substitution test. Only defined for participants who took a neurocognitive assessment (NEE form).

This variable is defined only for participants that have ECG data.

This variable is defined only for participants that have ECG data.

This variable is the sum of the scores of the first 3 trials of the SEVLT test. Only defined for participants who took a neurocognitive assessment (NEE form).

This variable is the scores of the 5th delayed recall trial of the SEVLT test. Definition per Dr. Hector Gonzalez. Only defined for participants who took a neurocognitive assessment (NEE form).

This variable is the total score of the 6-item screener, which uses recoding of the original responses per definitions by Dr. Hector Gonzalez. It can take integer values from 0 to 6. Only defined for participants who took a neurocognitive assessment (NEE form).

This variable is the sum of the score of the A and F parts of the Word Fluency test. Only defined for participants who took a neurocognitive assessment (NEE form).

This variable checks for medical history of stroke, mini-stroke or TIA, or balloon angioplasty or surgery to the arteries in the neck.

This variable indicates a self-report of diabetes.

Hypertension is defined here if the systolic or diastolic blood pressure is greater than or equal to 140/90 or if the participant is currently taking antihypertensive medications.

This variable calculates the ratio of total cholesterol by HDL cholesterol.

This variable estimated based on the estimated GFR value and is defined using NIDDK guidelines.

This variable checks for HDL, LDL, and triglyceride values to determine presence/absence of dyslipidemia.

This variable estimates Glomerular filtration rate, based on serum creatinine, and demographics gender, age and race (black vs. nonblack).

This variable estimates Glomerular filtration rate, based on serum cystatin C and no demographic factors.

This variable estimates Glomerular filtration rate, based on serum cystatin C, serum creatinine, and demographics gender, age and race (black vs. nonblack).