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Hispanic Community Health Study / Study of Latinos

Name Label Folder
airflow_limitation
Airflow Limitation (pre FEV1/FVC<70 only)
Airflow Limitation (pre FEV1/FVC<70 only)

This variable is based on the empirical evidence from the spirometry that the ratio of FEV1 to FVC is below the level defined by the ATS as indicative of restricted airflow. Defined only for valid spirometries.

Clinical Data/Diagnostic Studies/Lung Function
airflow_obstruction
Obstructive Lung Disease suspect
Obstructive Lung Disease suspect

This variable is based on the empirical evidence from the spirometry that the ratio of FEV1 to FVC is below the level defined by the ATS as indicative of restricted airflow.

Clinical Data/Diagnostic Studies/Lung Function
asthma_c4
4-level grouped Asthma Status
4-level grouped Asthma Status Clinical Data/Diagnostic Studies/Lung Function
asthma_c4_md
4-level grouped Asthma Status - by MD diagnosis
4-level grouped Asthma Status - by MD diagnosis Clinical Data/Diagnostic Studies/Lung Function
asthma_curr
Current Asthma
Current Asthma Clinical Data/Diagnostic Studies/Lung Function
asthma_curr_md
Currently have asthma with ever MD diagnosis
Currently have asthma with ever MD diagnosis Clinical Data/Diagnostic Studies/Lung Function
asthma_ever
Ever had Asthma (self-report)
Ever had Asthma (self-report) Clinical Data/Diagnostic Studies/Lung Function
asthma_ever_md
Ever had asthma with MD diagnosis
Ever had asthma with MD diagnosis Clinical Data/Diagnostic Studies/Lung Function
asthma_meds
Asthma Med Use - self/scanned (curr asthma by MD diag)
Asthma Med Use - self/scanned (curr asthma by MD diag)

This variable combines scanned/transcribed anti-asthmatic medication use with self-report asthma medication use.

Clinical Data/Diagnostic Studies/Lung Function
bd_response_abs
Bronchodilator Responsive by 15% change
Bronchodilator Responsive by 15% change

This variable is based on the post-bronchodilator measurement of the FEV1. The airflow remains restricted after the administration of albuterol the person did not respond by greater than a 15% improvement over their first measurement. If PRBA29 is not missing and POBA29 is not missing and PRBA29 > 0 then.

Clinical Data/Diagnostic Studies/Lung Function
copd_by_bd
COPD by BD Test
COPD by BD Test

This indicator of COPD is based on the post-bronchodilator measurement of the FEV1 to FVC ratio. The airflow remains restricted after the administration of albuterol.

Clinical Data/Diagnostic Studies/Lung Function
copd_by_bd_allpre
COPD by BD Test (for all valid PRE_BD)
COPD by BD Test (for all valid PRE_BD)

This variable is based on the post-bronchodilator measurement of the FEV1 to FVC ratio. The airflow remains restricted after the administration of albuterol. This variable is also defined for all participants who did not conduct a post-spirometry exam. Defined only for valid spirometries.

Clinical Data/Diagnostic Studies/Lung Function
copd_ever
Self-report of ever had COPD/Emph or CB
Self-report of ever had COPD/Emph or CB Clinical Data/Diagnostic Studies/Lung Function
copd_meds
COPD Med Use - self/scanned (ever COPD by MD diag)
COPD Med Use - self/scanned (ever COPD by MD diag)

This variable combines scanned/transcribed anti-asthmatic medication use with self-report COPD medication use.

Clinical Data/Diagnostic Studies/Lung Function
copd_self
Self-report of ever had COPD/Emph
Self-report of ever had COPD/Emph Clinical Data/Diagnostic Studies/Lung Function
fev1_fvc_ratio
FEV1/FVC Ratio
FEV1/FVC Ratio

This variable is the ratio of forced expiratory volume in one minute (FEV1 ) to forced vital capacity (FVC) expressed as a percentage.

Clinical Data/Diagnostic Studies/Lung Function
mrc_cb
Chronic Productive Cough 3+ mths in 2+ yrs
Chronic Productive Cough 3+ mths in 2+ yrs Clinical Data/Diagnostic Studies/Lung Function
phlegm
Phlegm day/night 3 months in a row
Phlegm day/night 3 months in a row Clinical Data/Diagnostic Studies/Lung Function
pneumonia
Pneumonia
Pneumonia Clinical Data/Diagnostic Studies/Lung Function
postbd_expected
Post-BD Expected (among valid spirometry
Post-BD Expected (among valid spirometry

This variable is a flag for whether a post bronchodilator was expected, based on the premeasurement. A post measurement was expected if the FEV1 to FVC ratio was less than 70% or less than the lower limit of normal for FEV1/FVC%.

Clinical Data/Diagnostic Studies/Lung Function
postbd_prebd_diff
Post(FEV1%pred)-Pre(FEV1%pred)
Post(FEV1%pred)-Pre(FEV1%pred)

This variable is based on the ratio of the measured FEV1 difference from postbronchodilator and pre-bronchodilator exams over the Predicted FEV1 calculated prebronch (both values must be non-missing, and the post-bronchodilator spirometry examinations must be valid).

Clinical Data/Diagnostic Studies/Lung Function
postbd_prebd_diff_gt12_v2
Post(FEV1%pred)-Pre(FEV1%pred)>=12% (pre FEV1/FVC<70 only)
Post(FEV1%pred)-Pre(FEV1%pred)>=12% (pre FEV1/FVC<70 only)

This variable is based on the ratio of the measured FEV1 difference from postbronchodilator and pre-bronchodilator exams over the Predicted FEV1 calculated prebronch (both values must be non-missing, and the post-bronchodilator spirometry examination must be valid) among participants with pre FEV1/FVC<70 only (ignores LLN comparison).

Clinical Data/Diagnostic Studies/Lung Function
valid_spirometry
Valid Spirometry Studies (Pre)
Valid Spirometry Studies (Pre)

This variable is an overall data quality indicator derived by the pulmonary reading center on the adequacy study for use.

Clinical Data/Diagnostic Studies/Lung Function
valid_spirometry_postbd
Valid Spirometry Studies (Post BD)
Valid Spirometry Studies (Post BD)

This variable is an overall data quality indicator derived by the pulmonary reading center on the adequacy study for use.

Clinical Data/Diagnostic Studies/Lung Function
valid_spirometry_postbd_v2
Valid post-spirometry (A-D grading) adjusted for unexpected BDs
Valid post-spirometry (A-D grading) adjusted for unexpected BDs

This variable is a flag for whether a post bronchodilator was valid (grade A-D). Defined only for participants where a post measurement was expected.

Clinical Data/Diagnostic Studies/Lung Function
wheeze_last12
Wheezing in last 12 months
Wheezing in last 12 months Clinical Data/Diagnostic Studies/Lung Function
wheeze_sb
Wheezing ever with shortness of breath
Wheezing ever with shortness of breath Clinical Data/Diagnostic Studies/Lung Function
digitsymbol
Digit Symbo Substitution Score (NEEA14)
Digit Symbo Substitution Score (NEEA14)

This variable is for the score of the digit symbol substitution test. Only defined for participants who took a neurocognitive assessment (NEE form).

Clinical Data/Diagnostic Studies/Neurocognitive
ecg_maj
Major ECG Abnormalities
Major ECG Abnormalities

This variable is defined only for participants that have ECG data.

Clinical Data/Diagnostic Studies/Neurocognitive
ecg_min
Minor ECG Abnormalities
Minor ECG Abnormalities

This variable is defined only for participants that have ECG data.

Clinical Data/Diagnostic Studies/Neurocognitive
no_disability_6item
No Diability on NEEA5-7
No Diability on NEEA5-7 Clinical Data/Diagnostic Studies/Neurocognitive
sevlt_3trials
SEVTL, Sum of 3 Trials (NEEA8=10)
SEVTL, Sum of 3 Trials (NEEA8=10)

This variable is the sum of the scores of the first 3 trials of the SEVLT test. Only defined for participants who took a neurocognitive assessment (NEE form).

Clinical Data/Diagnostic Studies/Neurocognitive
sevlt_recall
SEVLT, Delay Recall (NEEA11 with re-coding)
SEVLT, Delay Recall (NEEA11 with re-coding)

This variable is the scores of the 5th delayed recall trial of the SEVLT test. Definition per Dr. Hector Gonzalez. Only defined for participants who took a neurocognitive assessment (NEE form).

Clinical Data/Diagnostic Studies/Neurocognitive
total_6item
Total Score on 6 Item Screener (with re-coding)
Total Score on 6 Item Screener (with re-coding)

This variable is the total score of the 6-item screener, which uses recoding of the original responses per definitions by Dr. Hector Gonzalez. It can take integer values from 0 to 6. Only defined for participants who took a neurocognitive assessment (NEE form).

Clinical Data/Diagnostic Studies/Neurocognitive
wordfreq
Word Frequency (A+F) (NEEA12-13)
Word Frequency (A+F) (NEEA12-13)

This variable is the sum of the score of the A and F parts of the Word Fluency test. Only defined for participants who took a neurocognitive assessment (NEE form).

Clinical Data/Diagnostic Studies/Neurocognitive
cdcr_sueno
Cerebrovascular Disease and Carotid Revascularization, self-reported at the Sueno clinic visit
Cerebrovascular Disease and Carotid Revascularization, self-reported at the Sueno clinic visit

This variable checks for medical history of stroke, mini-stroke or TIA, or balloon angioplasty or surgery to the arteries in the neck.

Clinical Data/Incident Outcomes
diabetes_self_sueno
Diabetes - self report only, collected during the sueno clinic visit
Diabetes - self report only, collected during the sueno clinic visit

This variable indicates a self-report of diabetes.

Clinical Data/Incident Outcomes
diabetes_sueno
Diabetes (at Sueno visit) derived from SOL diagnosis and Sueno diabetes mellitus variables
Diabetes (at Sueno visit) derived from SOL diagnosis and Sueno diabetes mellitus variables Clinical Data/Incident Outcomes
hypertension_sueno
Hypertension at the Sueno visit as derived from the SOL diagnosis and Sueno hypertension variables
Hypertension at the Sueno visit as derived from the SOL diagnosis and Sueno hypertension variables

Hypertension is defined here if the systolic or diastolic blood pressure is greater than or equal to 140/90 or if the participant is currently taking antihypertensive medications.

Clinical Data/Incident Outcomes
cardiac_risk_ratio
Cardiac Risk Ratio (TC/HDL) - AHA
Cardiac Risk Ratio (TC/HDL) - AHA

This variable calculates the ratio of total cholesterol by HDL cholesterol.

Clinical Data/Laboratory Tests
ckd
Chronic Kidney Disease using eGFR only (NIDDK)
Chronic Kidney Disease using eGFR only (NIDDK)

This variable estimated based on the estimated GFR value and is defined using NIDDK guidelines.

Clinical Data/Laboratory Tests
dyslipidemia
Dyslipidemia (High LDL, low HDL, or high triglyerides) - NIH
Dyslipidemia (High LDL, low HDL, or high triglyerides) - NIH

This variable checks for HDL, LDL, and triglyceride values to determine presence/absence of dyslipidemia.

Clinical Data/Laboratory Tests
gfrscr
eGFR based on serum creatinine, gender, age and race
eGFR based on serum creatinine, gender, age and race

This variable estimates Glomerular filtration rate, based on serum creatinine, and demographics gender, age and race (black vs. nonblack).

Clinical Data/Laboratory Tests
gfrscys
eGFR based on serum cystatin C w/o demographics
eGFR based on serum cystatin C w/o demographics

This variable estimates Glomerular filtration rate, based on serum cystatin C and no demographic factors.

Clinical Data/Laboratory Tests
gfrscys_scr
eGFR based on serum cystatin C, serum creatinine, gender, age, and race
eGFR based on serum cystatin C, serum creatinine, gender, age, and race

This variable estimates Glomerular filtration rate, based on serum cystatin C, serum creatinine, and demographics gender, age and race (black vs. nonblack).

Clinical Data/Laboratory Tests
hba1c_si
Glycosylated Hemoglobin (HbA1c) in SI units (mmol/mol), nearest integer
Glycosylated Hemoglobin (HbA1c) in SI units (mmol/mol), nearest integer Clinical Data/Laboratory Tests
high_total_chol
Hypercholesterolemia (from LABA66,LABA68,LABA69,MED_LLD)
Hypercholesterolemia (from LABA66,LABA68,LABA69,MED_LLD)

This variable checks for Total cholesterol, HDL, LDL, and antihyperlipidemic medication use values to determine presence/absence of hypercholesterolemia.

Clinical Data/Laboratory Tests
homa_b
HOMA index of Beta Cell Function
HOMA index of Beta Cell Function

This variable defines the Homeostasis model assessment of insulin resistance.

Clinical Data/Laboratory Tests
homa_ir
HOMA index of Insulin Resistance
HOMA index of Insulin Resistance

This variable defines the Homeostasis model assessment of insulin resistance.

Clinical Data/Laboratory Tests
insulin_fast
Insulin, fasting (calibrated, converted to mU/L)
Insulin, fasting (calibrated, converted to mU/L)

This variable combines fasting glucose results from the central lab that was processed prior to July 5, 2010 (using units of mU/L) with results processed on or after July 5, 2010 (using units of pmol/L) and the overall units are converted to mU/L (1 mU/L = 6 pmol/L).

Clinical Data/Laboratory Tests
insulin_ogtt
Insulin, post OGTT (calibrated, converted to mU/L)
Insulin, post OGTT (calibrated, converted to mU/L)

This variable combines post OGTT glucose results from the central lab that were processed prior to July 5, 2010 (using units of mU/L) with results processed on or after July 5, 2010 (using units of pmol/L) and the overall units are converted to mU/L (1 mU/L = 6 pmol/L).

Clinical Data/Laboratory Tests
claudication_int
Intermittent Claudication - either leg
Intermittent Claudication - either leg

This variable defines intermittent claudication being present in either leg

Clinical Data/Vascular Measures
cvd_frame
Framingham CVD composite criterion
Framingham CVD composite criterion

This variable is an indicator that defines a composite CVD definition based on the Framingham Study criterion.

Clinical Data/Vascular Measures
frame_cvd_risk_10yr
Framingham CVD - 10 year risk (w/lab predictors)
Framingham CVD - 10 year risk (w/lab predictors)

This variable defines the Framingham CVD 10 year risk using lab predictors based on the Framingham Study criterion for participants. Individuals 30 to 74 years old only.

Clinical Data/Vascular Measures
abigrp_c4
4-level grouped Ankle Brachial Index (occ. failure incl.)
4-level grouped Ankle Brachial Index (occ. failure incl.)

This variable groups left and right ABI into 4 categories.

Clinical Data/Vital Signs/Seated Blood Pressure
abi_overall
Overall Ankle Branchial Index (occlusion failure included)
Overall Ankle Branchial Index (occlusion failure included)

Ankle Brachial Index (ABI) is the average ankle to arm systolic pressures as measured from the left and right sides. The higher of the two ankle measures on the same side is divided by the higher of the two systolic arm pressures to derive the right and left side ABI values. The overall ABI is the mean of those two measurements.

Clinical Data/Vital Signs/Seated Blood Pressure
left_abi
Left Ankle Branchial Index (occ. failure incl.)
Left Ankle Branchial Index (occ. failure incl.)

Ankle Brachial Index (ABI) is the average ankle to arm systolic pressures as measured from the left and right sides. The higher of the two ankle measures on the same side is divided by the higher of the two systolic arm pressures to derive the right and left side ABI values.

Clinical Data/Vital Signs/Seated Blood Pressure
left_abigrp_c4
Left 4-level grouped Ankle Brachial Index (occ. failure incl.)
Left 4-level grouped Ankle Brachial Index (occ. failure incl.)

This variable groups left and right ABI into 4 categories.

Clinical Data/Vital Signs/Seated Blood Pressure
right_abi
Right Ankle Branchial Index (occ. failure incl.)
Right Ankle Branchial Index (occ. failure incl.)

Ankle Brachial Index (ABI) is the average ankle to arm systolic pressures as measured from the left and right sides. The higher of the two ankle measures on the same side is divided by the higher of the two systolic arm pressures to derive the right and left side ABI values.

Clinical Data/Vital Signs/Seated Blood Pressure
right_abigrp_c4
Right 4-level grouped Ankle Brachial Index (occ. failure incl.)
Right 4-level grouped Ankle Brachial Index (occ. failure incl.)

This variable groups left and right ABI into 4 categories.

Clinical Data/Vital Signs/Seated Blood Pressure
sbpa5
Average seated systolic blood pressure based on three measurements at a single clinic visit, with an interval of 30 seconds between each measurement
Average seated systolic blood pressure based on three measurements at a single clinic visit, with an interval of 30 seconds between each measurement Clinical Data/Vital Signs/Seated Blood Pressure
sbpa6
Average seated diastolic blood pressure based on three measurements, with an interval of 30 seconds between each measurement
Average seated diastolic blood pressure based on three measurements, with an interval of 30 seconds between each measurement Clinical Data/Vital Signs/Seated Blood Pressure