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Honolulu-Asia Aging Study of Sleep Apnea

What

An assessment of the possible relationships between SDB and cognitive performance

Who

An elderly cohort of Japanese-American men under surveillance for Alzheimer disease

When

1999-2000 examination as part of a longitudinal study

Funding

National Institutes of Health

About

The Honolulu-Asia Aging Study of Sleep Apnea (HAASSA) was conducted to assess sleep-disordered breathing (SDB) in an elderly cohort of Japanese-American men under surveillance for Alzheimer disease (AD) and other dementias. Subjects had unattended overnight polysomnography (PSG) conducted in their home according to criteria established previously for the large multicenter Sleep Heart Health Study (SHHS). The protocol (conducted in 1999-2000) was added to the Honolulu-Asia Aging Study (HAAS), a longitudinal study of AD and other aspects of brain aging among surviving participants of the Honolulu Heart Program (HHP). More than 700 men aged 79 years and older were screened for dementia and received overnight PSG during the course of the 1999-2000 examination. These cross-sectional data were used to assess possible relationships between SDB and cognitive performance in late life.

Citation and acknowledgement

When using this dataset, please cite the following:

Zhang GQ, Cui L, Mueller R, Tao S, Kim M, Rueschman M, Mariani S, Mobley D, Redline S. The National Sleep Research Resource: towards a sleep data commons. J Am Med Inform Assoc. 2018 Oct 1;25(10):1351-1358. doi: 10.1093/jamia/ocy064. PMID: 29860441; PMCID: PMC6188513.

Foley DJ, Masaki K, White L, Larkin EK, Monjan A, Redline S. Sleep-disordered breathing and cognitive impairment in elderly Japanese-American men. Sleep. 2003 Aug 1;26(5):596-9. doi: 10.1093/sleep/26.5.596. PMID: 12938814.

Please include the following text in the Acknowledgements:

The Honolulu-Asia Aging Study of Sleep Apnea (HAASSA) was supported by contracts from the National Institute on Aging (NO1-AG-4-2149) and the National Heart, Lung, and Blood Institute (NO1-HC05102). The National Sleep Research Resource was supported by the National Heart, Lung, and Blood Institute (R24 HL114473, 75N92019R002).

Data overview

/datasets (introduction)
Core data from HAASSA.

/polysomnography (introduction)
Overnight polysomnography (PSG) data.

This dataset has special access restrictions. In order to access the polysomnography data and a limited dataset on the NSRR, a user must first obtain permission from the data owners at Kuakini Medical Center. Additional variables and data may be requested and obtained directly from the data owners.

In order to access the HAASSA data, please follow these steps:

  1. E-mail kssresearch@kuakini.org and request access to HAASSA data on the NSRR
  2. Once approved by the data owners, complete and submit a Data Access and Use Agreement

Equipment

National Sleep Research Resource
Honolulu-Asia Aging Study of Sleep Apnea