Sleep Heart Health Study

Participant taking ORAL STEROIDS within two weeks of the Sleep Heart Health Study Visit One (SHHS1) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking TRICYLIC ANTI-DEPRESSANTS within two weeks of the Sleep Heart Health Study Visit One (SHHS1) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking angiotensin-converting-enzyme inhibitor (ACE) INHIBITORS WITHOUT DIURETICS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking angiotensin-converting-enzyme inhibitor (ACE) INHIBITORS WITH DIURETICS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking BENZODIAZEPINES within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking BETA-BLOCKERS WITHOUT DIURETICS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking BETA-BLOCKERS WITH DIURETICS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ANY DIURETIC within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ANY ANTI-HYPERTENSIVE MEDICATION within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking INSULINS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking INHALED STEROIDS FOR ASTHMA within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ANY LIPID-LOWERING MEDICATION within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking MISCELLANEOUS LIPID-LOWERING DRUGS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ORAL ANTI-INFLAMMATORY ASTHMA DRUGS (LEUKOTRIENE RECEPTOR ANTAGONISTS AND INHIBITORS OF LIPO-OXYGENASE) within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ORAL HYPOGLYCEMIC AGENTS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking ORAL STEROIDS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Participant taking TRICYLIC ANTI-DEPRESSANTS within two weeks of the Sleep Heart Health Study Visit Two (SHHS2) visit. All medications were recorded during the interview, and medication information was later categorized by physician review.

Usual Alcohol Intake per day

Lifetime cigarette smoking: pack years

Parent Cohort reported Diabetes Status

1. Has a doctor ever told you that you have the following? a. Emphysema

1. Has a doctor ever told you that you have the following? b. Chronic bronchitis

1. Has a doctor ever told you that you have the following? c. chronic obstructive pulmonary disease (COPD)

1. Has a doctor ever told you that you have the following? d. Asthma

e. Do you still have asthma?

16. Has a doctor ever told you that you have the following? restless leg syndrome (RLS)?

Hypertension (HTN) Status based on 2nd and 3rd blood pressure readings OR being treated with hypertension (HTN) meds

Derived hypertension (HTN) classification (based on blood pressure measurements, history of hypertension (HTN) dx, and medication use)

Calculated - Summary metric of sleep disordered breathing events.

Calculated - Summary metric of sleep disordered breathing events. The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events.

Calculated - Summary metric of sleep disordered breathing events. The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events.

Calculated - Summary metric of sleep disordered breathing events.

Calculated - Summary metric of sleep disordered breathing events. The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Search for all AHI variables consistent with the same clinical guidelines within this dataset

Calculated - Summary metric of sleep disordered breathing events.

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events

Ratio of the count of all apneas (central and obstructive) and hypopneas associated with at least a >=4% oxygen desaturation to the total sleep time

Calculated - Summary metric of sleep disordered breathing events

Calculated - Summary metric of sleep disordered breathing events

Total number of arousals per hour of sleep. Ratio of count of arousals to total sleep time in hours.

Lowest oxygen saturation (SaO2)% during sleep

Overall study grade as assigned by scorer. These codes reflected the total duration of useable (artifact free, scorable) signals during sleep time across channels, weighing those signals most critical for accurate scoring of respiratory events and staging during sleep time. The Quality Assessment Form for SHHS2 was modified so that the overall quality grade and the signal quality codes were based on signals during sleep time. Since events were only scored during sleep time this provided a more accurate assessment of signal quality during the actual time or scoring. This change would only have affected the quality grade of a small number of studies in SHHS1 where there was a significant amount of time awake with very good signals combined with very poor signals that occurred during sleep. The overall and signal quality grades are comparable between SHHS1 and SHHS2.

Percent of sleep time in non-supine body position

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep (i.e. total sleep time, TST), while in-bed period is the interval between lights off/in-bed time and lights on/out-bed time (i.e. time in bed, TIB).Percentage of time in bed that was spent sleeping, or the ratio of total sleep time to total time in bed, expressed as a percentage.

Conventionally this variable would be called total sleep time (TST)(i.e. total time spent in stage 1 or greater).

The ratio of time in rapid eye movement sleep (REM) to total sleep time, expressed as a percentage.

Total amount of time spent awake after going to sleep

Calculated - Total score based on an 8-item questionnaires ranking likelihood of dozing off Johns MW 1991 (PubMed ID: 1798888). Scale 0-3 for individual items; 0 to 24 for overall score.

Search for all ESS variables within this dataset

Calculated - Total score based on an 8-item questionnaires ranking likelihood of dozing off Johns MW 1991 (PubMed ID: 1798888). Scale 0-3 for individual items; 0 to 24 for overall score.

Search for all ESS variables within this dataset

17. Have you ever been told by a doctor that you have a sleep disorder (other than sleep apnea)?

The Short Sleep Apnea Quality of Life Index (Short SAQLI) score

This participant ID matches what is present in Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC). From BioLINCC, this column may be called 'npptid'.

Units are not consistent across observations; use wtunits to determine proper unit.