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Wisconsin Sleep Cohort

Name Label Folder
vst_year
Year of polysomnography data collection
Year of polysomnography data collection Administrative
wsc_id
Unique identifier
Unique identifier

Randomly generated

Administrative
wsc_vst
Study visit number
Study visit number

Sequential visit

Administrative
bmi
Body mass index (BMI)
Body mass index (BMI) Anthropometry
weightkg
Weight
Weight

Record weight to the nearest 0.5 kg on mechanical beam scale.

Anthropometry
death_year
Death Year
Death Year Clinical Data/Incident Outcomes
dbp_mean
Mean of seated diastolic pressures
Mean of seated diastolic pressures

Mean of two standard seated blood pressure measurements on the night of the PSG. If repeat measurements were taken, the mean of the closest two measurements.

Clinical Data/Vital Signs
sbp_mean
Mean of seated systolic measures
Mean of seated systolic measures

Mean of two standard seated blood pressure measurements on the night of the PSG. If repeat measurements were taken, the mean of the closest two measurements.

Clinical Data/Vital Signs
age
Age of the participant
Age of the participant

Age at time of study visit

Demographics
race
Race of the participant
Race of the participant Demographics
sex
Sex of the participant
Sex of the participant Demographics
state
State-Trait Anxiety Inventory (State Anxiety Subscale) Score
State-Trait Anxiety Inventory (State Anxiety Subscale) Score

Sum of 20 items from State Anxiety Questionnaire. When there are 2 or less missing, the average of all of the other scores are used to create the sum variable

General Health/State Trait Anxiety Inventory
trait
Trait Anxiety Score
Trait Anxiety Score

Sum of 20 items from Trait Anxiety Questionnaire. When there are 2 or less missing, the average of all of the other scores are used to create the sum variable

General Health/State Trait Anxiety Inventory
zung_index
Standardized Zung Depression Scale Total Score
Standardized Zung Depression Scale Total Score

Scaled Zung Depression Scale score used with clinical cutpoints

General Health/Zung Depression Scale
nsrr_bmi
Body mass index (BMI)
Body mass index (BMI)

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bmi

Harmonized/Anthropometry
nsrr_bp_diastolic
Diastolic blood pressure
Diastolic blood pressure

Average resting diastolic blood pressure of two measurements collected from the upper arm in a single clinic visit.When more than two measurements were collected, the average was calculated using the two closest measurements.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: dbp_mean

Harmonized/Clinical Data
nsrr_bp_systolic
Systolic blood pressure
Systolic blood pressure

Average resting systolic blood pressure of two measurements collected from the upper arm in a single clinic visit. When more than two measurements were collected, the average was calculated using the two closest measurements.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sbp_mean

Harmonized/Clinical Data
nsrr_age
Subject age
Subject age

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age

Harmonized/Demographics
nsrr_age_gt89
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age

Harmonized/Demographics
nsrr_race
Subject race
Subject race

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: race

Harmonized/Demographics
nsrr_sex
Subject sex
Subject sex

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sex

Harmonized/Demographics
nsrr_current_smoker
Currently smoking cigarettes
Currently smoking cigarettes

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: smoke_curr

Harmonized/Lifestyle and Behavioral Health
nsrr_ever_smoker
Ever smoked cigarettes
Ever smoked cigarettes

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: smoke

Harmonized/Lifestyle and Behavioral Health
nsrr_ahi_hp4u_aasm15
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team.

The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Refer to the source for detailed definition for respiratory events: ahi

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ttldursp_f1
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography

Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater).

Harmonized by the NSRR team. Source: tst

Harmonized/Polysomnography/Sleep Architecture
mslt
MSLT Score
MSLT Score

Average of first four naps

Variable from a Multiple Sleep Latency Test (MSLT), Roehrs & Roth 1992 (PubMed ID: 1552009).

Search for all Multiple Sleep Latency Test variables within this dataset

Sleep Monitoring/Other Sleep Tests/Multiple Sleep Latency Test (MSLT)
ahi
Apnea-Hypopnea Index: (Apneas with no oxygen desaturation threshold used and with or without arousal and hypopneas with discernible flow reduction and with >= 4% oxygen desaturation and with or without arousal) / hours of sleep from type I polysomnography
Apnea-Hypopnea Index: (Apneas with no oxygen desaturation threshold used and with or without arousal and hypopneas with discernible flow reduction and with >= 4% oxygen desaturation and with or without arousal) / hours of sleep from type I polysomnography

Calculated - Summary metric of sleep disordered breathing events

Sleep Monitoring/Polysomnography
minsao2tst
Minimum level of oxygen saturation in total sleep duration from type I polysomnography
Minimum level of oxygen saturation in total sleep duration from type I polysomnography

Conventionally, total sleep duration would be called total sleep time (TST).

Sleep Monitoring/Polysomnography
ptstl90
Percent of the total sleep duration with oxygen saturation below 90% from type I polysomnography
Percent of the total sleep duration with oxygen saturation below 90% from type I polysomnography

Conventionally, total sleep duration would be called total sleep time (TST).

Sleep Monitoring/Polysomnography
se
Sleep Efficiency: the proportion of sleep duration in in-bed period from type I polysomnography
Sleep Efficiency: the proportion of sleep duration in in-bed period from type I polysomnography

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep (i.e. total sleep time, TST), while in-bed period is the interval between lights off/in-bed time and lights on/out-bed time (i.e. time in bed, TIB).

Sleep Monitoring/Polysomnography
tst
Total Sleep Duration: the interval between sleep onset time and lights on/out-bed time while the participant is asleep from type I polysomnography
Total Sleep Duration: the interval between sleep onset time and lights on/out-bed time while the participant is asleep from type I polysomnography

Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater).

Sleep Monitoring/Polysomnography
waso
Wake After Sleep Onset: the total duration between sleep onset and lights-on/out-bed time while being awake from type I polysomnography
Wake After Sleep Onset: the total duration between sleep onset and lights-on/out-bed time while being awake from type I polysomnography Sleep Monitoring/Polysomnography
ho_score
Modified Horne Ostberg Morningness-Eveningness Questionnaire Score
Modified Horne Ostberg Morningness-Eveningness Questionnaire Score

Calculated - Summary score derived based on modified Horne-Ostberg Morningness-Eveningness Questionnaire. Horne JA and Ostberg O, 1976 (PubMed ID: 1027738)

Search for all HOMEQ variables within this dataset

Sleep Questionnaires/Chronotype
ess
Epworth Sleepiness Scale: Total score
Epworth Sleepiness Scale: Total score

Calculated - Total score based on an 8-item questionnaire ranking likelihood of dozing off Johns MW 1991 (PubMed ID: 1798888). Scale 0-3 for individual items; 0 to 24 for overall score.

Search for all ESS variables within this dataset

Sleep Questionnaires/Hypersomnia
apnea
Sleep Apnea: Self-reported diagnosis by a physician
Sleep Apnea: Self-reported diagnosis by a physician

Have you ever been told by a doctor that you have sleep apnea?

Sleep Questionnaires/Sleep Disorder
tso
Self-reported sleep latency
Self-reported sleep latency

About how many minutes does it usually take you to fall asleep at night? _____#minutes

Sleep Questionnaires/Sleep Habits
apnea_treatment_year
Year of apnea treatment
Year of apnea treatment Administrative
headcm
Head circumference
Head circumference

Position the tape slightly above the eyebrows in a horizontal plane to the back of the head, measuring the maximum circumference. Make sure not to include large amounts of hair and hair accessories under the tape. Pull tape slightly to compress hair and record measurement to the nearest 0.5 cm

Anthropometry
heightcm
Height
Height

Height (without shoes) to the nearest cm. on mechanical beam scale with participant facing outward and measuring bar perpendicular to floor

Anthropometry
hip_girth1
First measurement of hip girth
First measurement of hip girth

Measure at largest circumference over the buttocks with participant standing erect with arms at side

Anthropometry
hip_girth2
Second measurement of hip girth
Second measurement of hip girth

Measure at largest circumference over the buttocks with participant standing erect with arms at side

Anthropometry
hipgirthm
Mean of hip girth measures
Mean of hip girth measures Anthropometry
neck_girth1
First measurement of neck girth
First measurement of neck girth

With participant sitting or standing erect, measure below 'Adam's Apple' at the smallest circumference of neck with tape perpendicular to the long axis of the neck

Anthropometry
neck_girth2
Second measurement of neck girth
Second measurement of neck girth

With participant sitting or standing erect, measure below 'Adam's Apple' at the smallest circumference of neck with tape perpendicular to the long axis of the neck

Anthropometry
neckgirthm
Mean of neck girth measures
Mean of neck girth measures Anthropometry
waist_girth1
First measurement of waist girth
First measurement of waist girth

With participant standing erect with arms at side and abdomen relaxed, measure at the smallest circumference near the navel and above the pelvis at the natural waistline. If no obvious waist, measure at the navel

Anthropometry
waist_girth2
Second measurement of waist girth
Second measurement of waist girth

With participant standing erect with arms at side and abdomen relaxed, measure at the smallest circumference near the navel and above the pelvis at the natural waistline. If no obvious waist, measure at the navel

Anthropometry
waistgirthm
Mean of waist girth measurements
Mean of waist girth measurements Anthropometry
waisthip
Waist to hip ratio
Waist to hip ratio Anthropometry
death_cause_1
Death cause #1
Death cause #1

Cause of death came from death certificates with an internal adjudication process to categorize cause of death into grouping for research purposes. Death certificate searches were completed on a regular basis. Due to delays in reporting of deaths and death searches, cause of death was not available for all known deaths; based on the last search, death year was available for deaths reported through 2017. (CVD = Cardiovascular Disease)

Clinical Data/Incident Outcomes
death_cause_2
Death cause #2
Death cause #2

Cause of death came from death certificates with an internal adjudication process to categorize cause of death into grouping for research purposes. Death certificate searches were completed on a regular basis. Due to delays in reporting of deaths and death searches, cause of death was not available for all known deaths; based on the last search, death year was available for deaths reported through 2017. (CVD = Cardiovascular Disease)

Clinical Data/Incident Outcomes
death_type_1
More Detail on Cause of Death #1
More Detail on Cause of Death #1

Afib=Atrial Fibrillation, Athero_HD=Atherosclerosis, CHF=Congestive Heart Failure, MI=Myocardial Infarction, Vfib=Ventricular Fibrillation, PE=Pulmonary Embolism, AD=Alzheimers Disease, UTI=Urinary Track Infection, COPD=Chronic Obstructive Pulmonary Disease, ESRD=End Stage Renal Disease

Clinical Data/Incident Outcomes
death_type_2
More Detail on Cause of Death #2
More Detail on Cause of Death #2

Afib=Atrial Fibrillation, Athero_HD=Atherosclerosis, CHF=Congestive Heart Failure, MI=Myocardial Infarction, Vfib=Ventricular Fibrillation, PE=Pulmonary Embolism, AD=Alzheimers Disease, UTI=Urinary Track Infection, COPD=Chronic Obstructive Pulmonary Disease, ESRD=End Stage Renal Disease

Clinical Data/Incident Outcomes
creatinine
Creatinine
Creatinine

Measure of creatinine level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
glucose
Glucose
Glucose

Measure of glucose level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
hdl
HDL Cholesterol
HDL Cholesterol

Measure of HDL level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
ldl
LDL Cholesterol
LDL Cholesterol

Measure of LDL level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
total_cholesterol
Total cholesterol
Total cholesterol

Measure of total cholesterol level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
triglycerides
Triglycerides
Triglycerides

Measure of triglyceride level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
uric_acid
Uric acid
Uric acid

Measure of uric acid level in blood, obtained from fasting blood draw on the morning after the overnight PSG

Clinical Data/Laboratory Tests
ankle_left1
First blood pressure from left ankle
First blood pressure from left ankle

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_left2
Second blood pressure from left ankle
Second blood pressure from left ankle

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_left_repeat
First repeat of blood pressure from left ankle, if needed
First repeat of blood pressure from left ankle, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_left_repeat2
Second repeat of blood pressure from left ankle, if needed
Second repeat of blood pressure from left ankle, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_right1
First blood pressure from right ankle
First blood pressure from right ankle

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_right2
Second blood pressure from right ankle
Second blood pressure from right ankle

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_right_repeat
First repeat of blood pressure from right ankle, if needed
First repeat of blood pressure from right ankle, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
ankle_right_repeat2
Second repeat of blood pressure from right ankle, if needed
Second repeat of blood pressure from right ankle, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_left1
First blood pressure from left arm
First blood pressure from left arm

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_left2
Second blood pressure from left arm
Second blood pressure from left arm

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_left_repeat
First repeat of blood pressure from left arm, if needed
First repeat of blood pressure from left arm, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_left_repeat2
Second repeat of blood pressure from left arm, if needed
Second repeat of blood pressure from left arm, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_right1
First blood pressure from right arm
First blood pressure from right arm

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_right2
Second blood pressure from right arm
Second blood pressure from right arm

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_right_repeat
First repeat of blood pressure from right arm, if needed
First repeat of blood pressure from right arm, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
arm_right_repeat2
Second repeat of blood pressure from right arm, if needed
Second repeat of blood pressure from right arm, if needed

Brachial blood pressure by Dopler at the overnight PSG

Clinical Data/Vital Signs
education_survey1
Highest education level completed by the participant
Highest education level completed by the participant Demographics/Education
shift_worker
Shift Worker (from Health Interview)
Shift Worker (from Health Interview) Demographics/Employment
eval_health
Self-reported general health
Self-reported general health

In general, would you say your health is (check one):

General Health
eval_life
Self-reported satisfaction with life
Self-reported satisfaction with life

How satisfied are you with the way you are spending your life (check one)?

General Health
zung10_scored
Zung Depression Scale Item: I get tired for no reason.
Zung Depression Scale Item: I get tired for no reason.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung11_scored
Zung Depression Scale Item: My mind is as clear as it used to be.
Zung Depression Scale Item: My mind is as clear as it used to be.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung12_scored
Zung Depression Scale Item: I find it easy to do the things I used to do.
Zung Depression Scale Item: I find it easy to do the things I used to do.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung13_scored
Zung Depression Scale Item: I am restless and can not keep still.
Zung Depression Scale Item: I am restless and can not keep still.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung14_scored
Zung Depression Scale Item: I feel hopeful about the future.
Zung Depression Scale Item: I feel hopeful about the future.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung15_scored
Zung Depression Scale Item: I am more irritable than usual.
Zung Depression Scale Item: I am more irritable than usual.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung16_scored
Zung Depression Scale Item: I find it easy to make decisions.
Zung Depression Scale Item: I find it easy to make decisions.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung17_scored
Zung Depression Scale Item: I feel that I am useful and needed.
Zung Depression Scale Item: I feel that I am useful and needed.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung18_scored
Zung Depression Scale Item: My life is pretty full.
Zung Depression Scale Item: My life is pretty full.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung19_scored
Zung Depression Scale Item: I feel that others would be better off if I were dead.
Zung Depression Scale Item: I feel that others would be better off if I were dead.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung1_scored
Zung Depression Scale Item: I feel down-hearted, blue and sad.
Zung Depression Scale Item: I feel down-hearted, blue and sad.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung20_scored
Zung Depression Scale Item: I still enjoy the things I used to do.
Zung Depression Scale Item: I still enjoy the things I used to do.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung2_scored
Zung Depression Scale Item: Morning is when I feel the best.
Zung Depression Scale Item: Morning is when I feel the best.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung3_scored
Zung Depression Scale Item: I have crying spells or feel like it.
Zung Depression Scale Item: I have crying spells or feel like it.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung4_scored
Zung Depression Scale Item: I have trouble sleeping through the night.
Zung Depression Scale Item: I have trouble sleeping through the night.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung5_scored
Zung Depression Scale Item: I eat as much as I used to.
Zung Depression Scale Item: I eat as much as I used to.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung6_scored
Zung Depression Scale Item: I enjoy looking at, talking to and being with attractive women/men.
Zung Depression Scale Item: I enjoy looking at, talking to and being with attractive women/men.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung7_scored
Zung Depression Scale Item: I notice that I am losing weight.
Zung Depression Scale Item: I notice that I am losing weight.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung8_scored
Zung Depression Scale Item: I have trouble with constipation.
Zung Depression Scale Item: I have trouble with constipation.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale
zung9_scored
Zung Depression Scale Item: My heart beats faster than usual.
Zung Depression Scale Item: My heart beats faster than usual.

Items from the Zung Depression Scale Zung WW 1965 (PubMed ID: 14221692)

Search for all Zung Depression Scale variables within this dataset

General Health/Zung Depression Scale