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MrOS Sleep Study

Name Label Folder
nsrrid
NSRR MrOS Participant Identifier
NSRR MrOS Participant Identifier

Obfuscated participant identifier provided for the NSRR by the MrOS Coordinating Center.

Administrative
visit
Visit
Visit Administrative
bpbpdiam
Average diastolic blood pressure
Average diastolic blood pressure Anthropometry
bpbpsysm
Average systolic blood pressure
Average systolic blood pressure Anthropometry
hwbmi
Body mass index
Body mass index Anthropometry
gender
Gender
Gender Demographics
gierace
Race/Ethnic Category
Race/Ethnic Category Demographics
girace
Race Category
Race Category Demographics
vs2age1
Age at Sleep Visit 2
Age at Sleep Visit 2

All ages greater than 89 have been recoded to 90

Demographics
vsage1
Age at Sleep Visit 1
Age at Sleep Visit 1

All ages greater than 89 have been recoded to 90

Demographics
nsrr_bmi
Body mass index (BMI)
Body mass index (BMI)

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: hwbmi at Visit 1

Harmonized/Anthropometry
nsrr_bp_diastolic
Diastolic blood pressure
Diastolic blood pressure

Average resting diastolic blood pressure of two measurements collected from the upper arm in a single clinic visit.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bpbpdiam at Visit 1

Harmonized/Clinical Data
nsrr_bp_systolic
Systolic blood pressure
Systolic blood pressure

Average resting systolic blood pressure of two measurements collected from the upper arm in a single clinic visit.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bpbpsysm at Visit 1

Harmonized/Clinical Data
nsrr_age
Subject age
Subject age

All ages greater than 89 have been recoded to 90. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: vsage1 at Visit 1

Harmonized/Demographics
nsrr_age_gt89
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years

All ages greater than 89 have been recoded to 90. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: vsage1 at Visit 1

Harmonized/Demographics
nsrr_ethnicity
Subject ethnicity
Subject ethnicity

Original missing value is recoded as "not reported".

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: gierace

Harmonized/Demographics
nsrr_race
Subject race
Subject race

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: gierace

Harmonized/Demographics
nsrr_sex
Subject sex
Subject sex

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: gender

Harmonized/Demographics
nsrr_current_smoker
Currently smoking cigarettes
Currently smoking cigarettes

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: tusmknow at Visit 1

Harmonized/Lifestyle and Behavioral Health
nsrr_ever_smoker
Ever smoked cigarettes
Ever smoked cigarettes

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: tursmoke at Visit 1

Harmonized/Lifestyle and Behavioral Health
nsrr_ahi_hp3r_aasm15
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team.

The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Refer to the source for detailed definition for respiratory events: poahi3a at Visit 1

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp3u
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: poahi3 at Visit 1

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4r
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: poahi4a at Visit 1

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4u_aasm15
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team.

The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Refer to the source for detailed definition for respiratory events: poahi4 at Visit 1

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_phrnumar_f1
Arousal Index: Number of arousals per hour of sleep from polysomnography
Arousal Index: Number of arousals per hour of sleep from polysomnography

Harmonized by the NSRR team. Source: poai_all at Visit 1

Harmonized/Polysomnography/Arousal
nsrr_flag_spsw
Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.
Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.

Harmonized by the NSRR team. Source: poprstag at Visit 1

Harmonized/Polysomnography/Signal Quality
nsrr_ttldursp_f1
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography

Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater).

Harmonized by the NSRR team. Source: poslprdp at Visit 1

Harmonized/Polysomnography/Sleep Architecture
pocpap
Did the participant use CPAP or BiPAP the night of the psg study?
Did the participant use CPAP or BiPAP the night of the psg study? Sleep Monitoring/Polysomnography/Evening and Morning Survey
poslpeff
Sleep Efficiency: the proportion of estimated sleep duration in in-bed period from type II polysomnography
Sleep Efficiency: the proportion of estimated sleep duration in in-bed period from type II polysomnography

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep (i.e. total sleep time, TST), while in-bed period is the interval between lights off/in-bed time and lights on/out-bed time (i.e. time in bed, TIB).

Sleep Monitoring/Polysomnography/Sleep Architecture
poslprdp
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from type II polysomnography
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from type II polysomnography

Conventionally this variable would be called total sleep time (TST)(i.e. total time spent in stage 1 or greater).

Sleep Monitoring/Polysomnography/Sleep Architecture
powaso
Wake after Sleep Onset: the total duration between sleep onset and sleep offset time while being awake from type II polysomnography
Wake after Sleep Onset: the total duration between sleep onset and sleep offset time while being awake from type II polysomnography Sleep Monitoring/Polysomnography/Sleep Architecture
epepwort
Epworth Sleepiness Scale: Total score
Epworth Sleepiness Scale: Total score

Calculated - Total score based on an 8-item questionnaires ranking likelihood of dozing off Johns MW 1991 (PubMed ID: 1798888). Scale 0-3 for individual items; 0 to 24 for overall score.

Search for all ESS variables within this dataset

Sleep Questionnaires/Hypersomnia
fofosq
Functional Outcomes of Sleep: Global Score (5-20)
Functional Outcomes of Sleep: Global Score (5-20)

Summary score based on the sum of the subscale scores of the Functional Outcomes of Sleep Questionnaire, with potential range of 5 to 20. A lower score suggests greater function impairment. Weaver et. al, 1997 (Pubmed ID: 9415942)

Search for all Functional Outcomes of Sleep variables within this dataset

Sleep Questionnaires/Sleep Disturbance
bparm
Blood pressure: Arm used
Blood pressure: Arm used Anthropometry
bpbp
Sitting blood pressure measurement 1
Sitting blood pressure measurement 1 Anthropometry
bpbp2
Sitting blood pressure measurement 2
Sitting blood pressure measurement 2 Anthropometry
bpbpdia
Sitting measurement 1: Diastolic
Sitting measurement 1: Diastolic Anthropometry
bpbpdia2
Sitting measurement 2: Diastolic
Sitting measurement 2: Diastolic Anthropometry
bpbpsys
Sitting measurement 1: Systolic
Sitting measurement 1: Systolic Anthropometry
bpbpsys2
Sitting measurement 2: Systolic
Sitting measurement 2: Systolic Anthropometry
bpcuff
Cuff size
Cuff size Anthropometry
bptrcf
Cuff size for BpTru
Cuff size for BpTru Anthropometry
hw1s2bmi
Body mass index, V1 to VS2
Body mass index, V1 to VS2 Anthropometry
hw1s2ht
Change in average height, V1 to VS2
Change in average height, V1 to VS2 Anthropometry
hw1s2wpc
Percent change in average weight, V1 to VS2
Percent change in average weight, V1 to VS2 Anthropometry
hw1s2wt
Change in average weight, V1 to VS2
Change in average weight, V1 to VS2 Anthropometry
hw1sbmi
Body mass index, V1 to sleep
Body mass index, V1 to sleep Anthropometry
hw1sht
Change in average height, V1 to sleep
Change in average height, V1 to sleep Anthropometry
hw1swt
Change in average weight, V1 to sleep
Change in average weight, V1 to sleep Anthropometry
hw1swtpc
Percent change in average weight, V1 to sleep
Percent change in average weight, V1 to sleep Anthropometry
hw2s2bmi
Body mass index, V2 to VS2
Body mass index, V2 to VS2 Anthropometry
hw2s2ht
Change in average height, V2 to VS2
Change in average height, V2 to VS2 Anthropometry
hw2s2wpc
Percentage change in average weight, V2 to VS2
Percentage change in average weight, V2 to VS2 Anthropometry
hw2s2wt
Change in average weight, V2 to VS2
Change in average weight, V2 to VS2 Anthropometry
hw3s2bmi
Body mass index, V3 to VS2
Body mass index, V3 to VS2 Anthropometry
hw3s2hip
Change in average hip circumference, V3 to VS2
Change in average hip circumference, V3 to VS2 Anthropometry
hw3s2ht
Change in average height, V3 to VS2
Change in average height, V3 to VS2 Anthropometry
hw3s2nck
Change in average neck circumference, V3 to VS2
Change in average neck circumference, V3 to VS2 Anthropometry
hw3s2wpc
Percentage change in average weight, V3 to VS2
Percentage change in average weight, V3 to VS2 Anthropometry
hw3s2wst
Change in average waist circumference, V3 to VS2
Change in average waist circumference, V3 to VS2 Anthropometry
hw3s2wt
Change in average weight, V3 to VS2
Change in average weight, V3 to VS2 Anthropometry
hwcircum
Were circumferences measured
Were circumferences measured Anthropometry
hwds2bmi
Body mass index, VD to VS2
Body mass index, VD to VS2 Anthropometry
hwds2ht
Change in average height, VD to VS2
Change in average height, VD to VS2 Anthropometry
hwds2wpc
Percentage change in average weight, VD to VS2
Percentage change in average weight, VD to VS2 Anthropometry
hwds2wt
Change in average weight, VD to VS2
Change in average weight, VD to VS2 Anthropometry
hwdsbmi
Body mass index, VD to sleep
Body mass index, VD to sleep Anthropometry
hwdsht
Change in average height, VD to sleep
Change in average height, VD to sleep Anthropometry
hwdswt
Change in average weight, VD to sleep
Change in average weight, VD to sleep Anthropometry
hwdswtpc
Percentage change in average weight, VD to sleep
Percentage change in average weight, VD to sleep Anthropometry
hwgt4
Do measurement 1 and measurement 2 differ by 4 or more millimeters?
Do measurement 1 and measurement 2 differ by 4 or more millimeters? Anthropometry
hwheight
Was height measured
Was height measured Anthropometry
hwhgt
Average height, standing
Average height, standing Anthropometry
hwhip
Average hip circumference
Average hip circumference Anthropometry
hwhip1
Hip, measurement 1
Hip, measurement 1 Anthropometry
hwhip2
Hip, measurement 2
Hip, measurement 2 Anthropometry
hwhip3
Hip, measurement 3
Hip, measurement 3 Anthropometry
hwkyph
Is the participant standing sideways due to kyphosis?
Is the participant standing sideways due to kyphosis? Anthropometry
hwmeas1
Standing height, measurement 1
Standing height, measurement 1 Anthropometry
hwmeas2
Standing height, measurement 2
Standing height, measurement 2 Anthropometry
hwmeas3
Standing height, measurement 3
Standing height, measurement 3 Anthropometry
hwmeas4
Standing height, measurement 4
Standing height, measurement 4 Anthropometry
hwneck
Average neck circumference
Average neck circumference Anthropometry
hwneck1
Neck, measurement 1
Neck, measurement 1 Anthropometry
hwneck2
Neck, measurement 2
Neck, measurement 2 Anthropometry
hwneck3
Neck, measurement 3
Neck, measurement 3 Anthropometry
hwpulse
Was pulse obtained?
Was pulse obtained? Anthropometry
hwpulse1
Pulse measurement 1
Pulse measurement 1 Anthropometry
hwpulse2
Pulse measurement 2
Pulse measurement 2 Anthropometry
hwpulsem
Mean pulse
Mean pulse Anthropometry
hwpulset
Pulse 1 + pulse 2
Pulse 1 + pulse 2 Anthropometry
hwss2bmi
Body mass index, SL to VS2
Body mass index, SL to VS2 Anthropometry
hwss2hip
Change in average hip circumference, sleep to VS2
Change in average hip circumference, sleep to VS2 Anthropometry
hwss2ht
Change in average height, sleep to VS2
Change in average height, sleep to VS2 Anthropometry
hwss2nck
Change in average neck circumference, sleep to VS2
Change in average neck circumference, sleep to VS2 Anthropometry
hwss2wpc
Percentage change in average weight, sleep to VS2
Percentage change in average weight, sleep to VS2 Anthropometry
hwss2wst
Change in average waist circumference, sleep to VS2
Change in average waist circumference, sleep to VS2 Anthropometry
hwss2wt
Change in average weight, sleep to VS2
Change in average weight, sleep to VS2 Anthropometry
hwwais
Average waist circumference
Average waist circumference Anthropometry
hwwais1
Waist, measurement 1
Waist, measurement 1 Anthropometry