crossover eligible

Related Variables

treatmentarm Treatment arm

Subjects were randomized to a treatment arm (i.e. diagnostic study type) at the end of the Baseline Visit.

 		Administrative
ahige15 Apnea-Hypopnea Index (AHI) >= 15 on diagnostic sleep study Sleep Monitoring/Administrative
diagtype Diagnostic type used to determine Apnea-Hypopnea Index (AHI) Sleep Monitoring/Polysomnography/Administrative
ahi Apnea-Hypopnea Index (AHI): (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation ) / hour of sleep from type I polysomnography or type III home sleep test

Composite AHI based on the diagnostic sleep study and home sleep study.

The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Search for all AHI variables consistent with the same clinical guidelines within this dataset

 		Sleep Monitoring/Polysomnography/Apnea-Hypopnea Indices
ahi_d Apnea-Hypopnea Index (AHI) (split-night, diagnostic): (All apneas with no oxygen desaturation threshold used and with or without arousal+ hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation and with or without arousal ) / hour of sleep from type I polysomnography

Calculated - Summary metric of sleep disordered breathing events. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Search for all AHI variables consistent with the same clinical guidelines within this dataset

 		Sleep Monitoring/Polysomnography/Apnea-Hypopnea Indices
avghr_d Average heart rate during sleep from type I polysomnography (split-night, diagnostic) Sleep Monitoring/Polysomnography/Heart Rate
avgsao2_d Average oxygen saturation during sleep from type I polysomnography (split-night, diagnostic) Sleep Monitoring/Polysomnography/Oxygen Saturation
pctrem_d Percent of total sleep duration in REM sleep from type I polysomnography (split-night, diagnostic)

Conventionally, total sleep duration would be called total sleep time (TST).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
pctsa90p_d Portion of sleep time spent with oxygen saturation less than 90% (split-night, diagnostic)

Conventionally, total sleep duration would be called total sleep time (TST).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
pctstg1_d Percentage of stage 1 sleep among total sleep duration from type I polysomnography (split-night, diagnostic)

Conventionally, total sleep duration would be called total sleep time (TST).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
pctstg2_d Percentage of stage 2 sleep among total sleep duration from type I polysomnography (split-night, diagnostic)

Conventionally, total sleep duration would be called total sleep time (TST).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
pctstg34_d Percentage of stage 3/4 sleep among total sleep duration from type I polysomnography (split-night, diagnostic)

Conventionally, total sleep duration would be called total sleep time (TST).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
slpeff_d Sleep Efficiency (split-night, diagnostic): the ratio of sleep duration (i.e. total sleep time) to in-bed period from type I polysomnography

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep (i.e. total sleep time, TST), while in-bed period is the interval between lights off/in-bed time and lights on/out-bed time (i.e. time in bed, TIB).

 		Sleep Monitoring/Polysomnography/Sleep Architecture
slpprd_d Total sleep duration from type I polysomnography (split-night, diagnostic)

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep, conventionally called total sleep time.

This time period is used to calculate indices and other averages.

 		Sleep Monitoring/Polysomnography/Sleep Architecture
tst_modified Total sleep duration from type I polysomnography and type III home sleep test

Composite total sleep duration based on the diagnostic sleep study and home sleep study.

Sleep duration is the interval between sleep onset time and lights on/out-bed time while asleep, conventionally called total sleep time. For participants from the type III home sleep test, it is based on estimated sleep duration, which provides an approximation of total sleep duration (i.e. total sleep time) inferred from analysis of non-EEG channels Zhao et al., 2017 (PMID:27707441)

This time period is used to calculate indices and other averages.

 		Sleep Monitoring/Polysomnography/Sleep Architecture