Name	Label	Folder
nsrr_bmi Body mass index (BMI)	Body mass index (BMI) Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bmi at Visit 3	Harmonized/Anthropometry
nsrr_bp_diastolic Diastolic blood pressure	Diastolic blood pressure Average resting diastolic blood pressure of six measurements (three measurements in the evening and three in the morning) collected from the upper arm in a single day. In cases where either of the measurements was missing, the average was calculated discarding the missing value. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bpdias at Visit 3	Harmonized/Clinical Data
nsrr_bp_systolic Systolic blood pressure	Systolic blood pressure Average resting systolic blood pressure of six measurements (three measurements in the evening and three in the morning) collected from the upper arm in a single day. In cases where either of the measurements was missing, the average was calculated discarding the missing value. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bpsys at Visit 3	Harmonized/Clinical Data
nsrr_age Subject age	Subject age Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 3	Harmonized/Demographics
nsrr_age_gt89 Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years	Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 3	Harmonized/Demographics
nsrr_ethnicity Subject ethnicity	Subject ethnicity Original missing value is recoded as "not reported". Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: ethnicity at Visit 3	Harmonized/Demographics
nsrr_race Subject race	Subject race Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: race at Visit 3	Harmonized/Demographics
nsrr_sex Subject sex	Subject sex Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: male at Visit 3	Harmonized/Demographics
nsrr_current_smoker Currently smoking cigarettes	Currently smoking cigarettes Indicates whether subject currently smokes cigarettes. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: yevrsmk , ycursmk at Visit 3	Harmonized/Lifestyle and Behavioral Health
nsrr_ever_smoker Ever smoked cigarettes	Ever smoked cigarettes Indicates whether subject ever regularly smoked cigarettes. Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: yevrsmk at Visit 3	Harmonized/Lifestyle and Behavioral Health
nsrr_ahi_hp3r_aasm15 Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep	Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep Harmonized by the NSRR team. The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.] Refer to the source for detailed definition for respiratory events: ahi_a0h3a at Visit 3	Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp3u Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep	Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: ahi_a0h3 at Visit 3	Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4r Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep	Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: ahi_a0h4a at Visit 3	Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4u_aasm15 Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep	Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep Harmonized by the NSRR team. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]. Refer to the source for detailed definition for respiratory events: ahi_a0h4 at Visit 3	Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_phrnumar_f1 Arousal Index: Number of arousals per hour of sleep from polysomnography	Arousal Index: Number of arousals per hour of sleep from polysomnography Harmonized by the NSRR team. Source: ai_all at Visit 3	Harmonized/Polysomnography/Arousal
nsrr_flag_spsw Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.	Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored. Harmonized by the NSRR team. Source: slewake at Visit 3	Harmonized/Polysomnography/Signal Quality
nsrr_ttldursp_f1 Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography	Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater). Harmonized by the NSRR team. Source: slpprdp at Visit 3	Harmonized/Polysomnography/Sleep Architecture

Cleveland Children's Sleep and Health Study