The Best Apnea Interventions for Research (BestAIR) study aimed to randomize approximately 180 patients with sleep apnea who had either established CVD or at least three CVD risk factors into a 12-mo, four-arm intervention study. All arms included nightly use of nasal dilator strips and conservative medical therapy (CMT) defined as education on healthy sleep and lifestyle. The two active arms were: (1) active CPAP delivered using standard support from a trained sleep technician; and (2) active CPAP enhanced by a behavioral promotion intervention delivered by a behavioral therapist. The two control arms were: (1) sham-CPAP; and (2) CMT alone. The primary physiological outcome was change in mean 24-h systolic blood pressure. Process measures were recruitment yields, retention rates, and CPAP adherence levels.
Read more about BestAIR at ClinicalTrials.gov (NCT01261390).
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Please include the following text in the Acknowledgements:
The Best Apnea Interventions in Research (BestAIR) was supported by the National Heart, Lung, and Blood Institute (1U34HL105277) and a grant from ResMed Foundation. Equipment was donated by ResMed and Philips Respironics. The National Sleep Research Resource was supported by the National Heart, Lung, and Blood Institute (R24 HL114473, 75N92019R002).
/datasets (introduction)
Core data from baseline and follow-up visits.
/polysomnography (introduction)
Overnight polysomnography (PSG) data from baseline and follow-up visits.